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Anne Lingford-Hughes, BM, PhD, MRCPsych

Imperial College London, and Central North West London NHS Foundation Trust, London, UK

Anne Lingford-Hughes is Professor of Addiction Biology at Imperial College London, a post she has held since 2009. She is also a Consultant Psychiatrist at Central North West London NHS Foundation Trust, with a particular interest in pharmacological treatments of alcohol problems and comorbidity. Professor Lingford-Hughes graduated in medicine from Oxford University, Oxford, UK, and completed her PhD at Cambridge University, Cambridge, UK, following this with postdoctoral research at the National Institute of Mental Health in the USA. She trained in psychiatry at The Bethlem Royal and Maudsley Hospitals and Institute of Psychiatry, Beckenham and London, UK.

Professor Lingford-Hughes’ research has focused on using PET and fMRI neuroimaging and neuropharmacological challenges to characterize the neurobiology of addiction, particularly alcoholism and opiate dependence. She is currently working on Medical Research Council (MRC)-funded studies into the pharmacology of different vulnerabilities to relapse in alcohol, heroin, and cocaine addiction and on the role of the opioid system in gambling and alcoholism. In addition she is leading a trial investigating whether baclofen is a useful adjunct to benzodiazepines in gamma-hydroxybutyrate (GHB) withdrawal.

Professor Lingford-Hughes has also contributed to National Institute for Health and Care Excellence (NICE) guidelines on treating alcohol and opiate addiction. She led the process of setting up the British Association for Psychopharmacology (BAP) guidelines on addiction, as well as contributing to guidelines on comorbidities of addiction. She is currently Vice-Chair of the Academic Faculty of the Royal College of Psychiatrists. 

Lectures & interviews

  • Neurobiology of alcohol dependence

    Alcohol dependence is a brain disease with a progressive, and relapsing, course. Increased understanding of the neurobiology of alcohol dependence...